Trichloroacetic Acid → 2,2,2-trichloro-N-[[3-[4-[4-(1-cyanoethylidene)piperidin-1-yl]-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

HRID 295496Notes

Reaction equation

HRID 295496 reaction equation
[C:1](#[N:2])[C:3]([CH3:4])=[C:5]1[CH2:6][CH2:7][N:8]([c:11]2[c:12]([F:25])[cH:13][c:14]([N:17]3[C:18](=[O:24])[O:19][CH:20]([CH2:22][NH2:23])[CH2:21]3)[cH:15][cH:16]2)[CH2:9][CH2:10]1.[OH:26][C:27](=[O:28])[C:29]([Cl:30])([Cl:31])[Cl:32]>>[C:1](#[N:2])[C:3]([CH3:4])=[C:5]1[CH2:6][CH2:7][N:8]([c:11]2[c:12]([F:25])[cH:13][c:14]([N:17]3[C:18](=[O:24])[O:19][CH:20]([CH2:22][NH:23][C:27](=[O:26])[C:29]([Cl:30])([Cl:31])[Cl:32])[CH2:21]3)[cH:15][cH:16]2)[CH2:9][CH2:10]1

Participants

3

Reactant 2

HCID 6421Trichloroacetic AcidHCID 693154362-[1-[4-[5-(Aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]-2-fluorophenyl]piperidin-4-ylidene]propanenitrile

Product 1

HCID 693121402,2,2-trichloro-N-[[3-[4-[4-(1-cyanoethylidene)piperidin-1-yl]-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

Sources & evidence

ORD record
ord-d803daa8b3e0404d99090363d83ba8a0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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