Hydrochloric Acid → 1-[3-[4-(4-fluorobenzoyl)-1-piperidinyl]propyl]-2,3-dihydro-2,2-dimethyl-4(1H)-quinazolinone
Reaction equation
[CH3:43][CH:44]([CH3:45])[CH2:46][C:47](=[O:48])[CH3:49].[Cl:1][CH2:2][CH2:3][CH2:4][N:5]1[C:6]([CH3:16])([CH3:17])[NH:7][C:8](=[O:15])[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]21.[ClH:18].[F:19][c:20]1[cH:21][cH:22][c:23]([C:26](=[O:27])[CH:28]2[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]2)[cH:24][cH:25]1.[I-:41].[K+:40].[Na+:34].[Na+:35].[O-:36][C:37](=[O:38])[O-:39].[OH2:42]>>[CH2:2]([CH2:3][CH2:4][N:5]1[C:6]([CH3:16])([CH3:17])[NH:7][C:8](=[O:15])[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]21)[N:31]1[CH2:30][CH2:29][CH:28]([C:26]([c:23]2[cH:22][cH:21][c:20]([F:19])[cH:25][cH:24]2)=[O:27])[CH2:33][CH2:32]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-3274a9cba76e4bc4a7811e5f6a40ea4d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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