Dichloromethane → 3-(RS)-Cinnamoylamino-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one
Reaction equation
[C:21]([CH:22]=[CH:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)(=[O:30])[Cl:31].[CH2:39]([Cl:40])[Cl:41].[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[NH2:1][CH:2]1[C:3](=[O:20])[NH:4][c:5]2[c:6]([cH:16][cH:17][cH:18][cH:19]2)[C:7]([c:9]2[c:10]([F:15])[cH:11][cH:12][cH:13][cH:14]2)=[N:8]1>>[NH:1]([CH:2]1[C:3](=[O:20])[NH:4][c:5]2[c:6]([cH:16][cH:17][cH:18][cH:19]2)[C:7]([c:9]2[c:10]([F:15])[cH:11][cH:12][cH:13][cH:14]2)=[N:8]1)[C:21]([CH:22]=[CH:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)=[O:30]Participants
5
Sources & evidence
- ORD record
- ord-02a68bdeb5f14477b254fa94f0cb059e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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