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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 295725Generated: October 31, 2026

Water → 4-Chloro-2-(trifluoromethyl)nicotinic acid

https://huagongshe.com/reaction/295725

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantPyridineHCID 1049—
ReactantHexachloroethaneHCID 6214—
ReactantTetrahydrofuranHCID 8028—
Reactant2,2,6,6-TetramethylpiperidineHCID 13035—
Reactant2-(Trifluoromethyl)pyridine-3-carboxylic acidHCID 2777547—
ReactantButyllithiumHCID 178418339—
Product4-Chloro-2-(trifluoromethyl)nicotinic acidHCID 59553896—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-f0263b5d3f33415688574b50cbe9a5bd
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)