Methanol → 5,7-dichloro-3-(4-methoxy-3-nitro-phenyl)-3-methyl-1H-quinoline-2,4-dione

HRID 295762Notes

Reaction equation

HRID 295762 reaction equation
[CH3:1][O:2][C:3]([c:4]1[c:5]([NH:12][C:13]([CH:14]([CH3:15])[c:16]2[cH:17][c:18]([N+:24](=[O:25])[O-:26])[c:19]([O:22][CH3:23])[cH:20][cH:21]2)=[O:27])[cH:6][c:7]([Cl:11])[cH:8][c:9]1[Cl:10])=[O:28].[CH3:30][Si:31]([N-:32][Si:33]([CH3:34])([CH3:35])[CH3:36])([CH3:37])[CH3:38].[CH3:42][OH:43].[Cl:39][CH2:40][Cl:41].[Li+:29]>>[O:2]=[C:3]1[c:4]2[c:5]([cH:6][c:7]([Cl:11])[cH:8][c:9]2[Cl:10])[NH:12][C:13](=[O:27])[C:14]1([CH3:15])[c:16]1[cH:17][c:18]([N+:24](=[O:25])[O-:26])[c:19]([O:22][CH3:23])[cH:20][cH:21]1

Participants

6

Reactant 5

HCID 887MethanolHCID 6344DichloromethaneHCID 28486Lithium ionHCID 3280088Npc316347HCID 688191894,6-Dichloro-2-[2-(4-methoxy-3-nitro-phenyl)-propionylamino]-benzoic acid methyl ester

Product 1

HCID 116540895,7-dichloro-3-(4-methoxy-3-nitro-phenyl)-3-methyl-1H-quinoline-2,4-dione

Sources & evidence

ORD record
ord-f293d1f04e914a14a58c6515c0263550
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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