Bromide ion → 1-[4-[4-Chloro-2-(1-hydroxyethyl)-5-methoxyphenyl]piperazin-1-yl]-2-[4-chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanone
Reaction equation
[Br-:32].[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:33][Mg+:34].[CH3:35][CH2:36][O:37][CH2:38][CH3:39].[Cl:1][c:2]1[c:3]([O:30][CH3:31])[cH:4][c:5]([N:10]2[CH2:11][CH2:12][N:13]([C:16]([CH2:17][n:18]3[n:19][c:20]([C:25]([F:26])([F:27])[F:28])[c:21]([Cl:24])[c:22]3[CH3:23])=[O:29])[CH2:14][CH2:15]2)[c:6]([CH:7]=[O:8])[cH:9]1>>[Cl:1][c:2]1[c:3]([O:30][CH3:31])[cH:4][c:5]([N:10]2[CH2:11][CH2:12][N:13]([C:16]([CH2:17][n:18]3[n:19][c:20]([C:25]([F:26])([F:27])[F:28])[c:21]([Cl:24])[c:22]3[CH3:23])=[O:29])[CH2:14][CH2:15]2)[c:6]([CH:7]([OH:8])[CH3:35])[cH:9]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f45bbe83b5e54587b4087e5d4bef880e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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