Dichloromethane → [4-[[6-(2,3-dihydro-1H-inden-1-ylamino)pyrimidin-4-yl]amino]-2-hydroxycyclopentyl]methyl sulfamate

HRID 296167Notes

Reaction equation

HRID 296167 reaction equation
[CH:1]1([NH:10][c:11]2[cH:12][c:13]([NH:17][CH:18]3[CH2:19][CH:20]([OH:36])[CH:21]([CH2:23][O:24][S:25](=[O:26])(=[O:27])[NH:28][C:29](=[O:30])[O:31][C:32]([CH3:33])([CH3:34])[CH3:35])[CH2:22]3)[n:14][cH:15][n:16]2)[CH2:2][CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21.[Cl:44][CH2:45][Cl:46].[OH:37][C:38]([C:39]([F:40])([F:41])[F:42])=[O:43]>>[CH:1]1([NH:10][c:11]2[cH:12][c:13]([NH:17][CH:18]3[CH2:19][CH:20]([OH:36])[CH:21]([CH2:23][O:24][S:25](=[O:26])(=[O:27])[NH2:28])[CH2:22]3)[n:14][cH:15][n:16]2)[CH2:2][CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 178454380HCID 178454380, compound

Product 1

HCID 178514793[4-[[6-(2,3-dihydro-1H-inden-1-ylamino)pyrimidin-4-yl]amino]-2-hydroxycyclopentyl]methyl sulfamate

Sources & evidence

ORD record
ord-ae15428a54ad40eeb2f08c5ddf376e3c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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