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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 296174Generated: October 26, 2026

Chloride → 8-(3-Cyclopropyl-propionyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

https://huagongshe.com/reaction/296174

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantHeptaneHCID 8900—
Reactant4-(Trifluoromethoxy)anilineHCID 600848—
ReactantDimethylalumanyliumHCID 16685399—
Reactant1-(3-Cyclopropyl-propionyl)-4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl esterHCID 66787019—
Product8-(3-Cyclopropyl-propionyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 49801959—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-56121026e96b49a19e24b96e8ab489bf
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)