Chloride → 8-(3-Cyclopropyl-propionyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one
Reaction equation
[CH2:1]([O:2][C:4](=[O:5])[C:6]1([CH2:19][CH2:20][O:3][CH3:21])[CH2:7][CH2:8][N:9]([C:12]([CH2:13][CH2:14][CH:15]2[CH2:16][CH2:17]2)=[O:18])[CH2:10][CH2:11]1)[CH3:22].[CH3:24][Al+:25][CH3:26].[CH3:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH3:45].[Cl-:23].[F:27][C:28]([O:29][c:30]1[cH:31][cH:32][c:33]([NH2:34])[cH:35][cH:36]1)([F:37])[F:38]>>[C:4]1(=[O:5])[C:6]2([CH2:7][CH2:8][N:9]([C:12]([CH2:13][CH2:14][CH:15]3[CH2:16][CH2:17]3)=[O:18])[CH2:10][CH2:11]2)[CH2:19][CH2:20][N:34]1[c:33]1[cH:32][cH:31][c:30]([O:29][C:28]([F:27])([F:37])[F:38])[cH:36][cH:35]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-56121026e96b49a19e24b96e8ab489bf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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