Imidazole → Ethyl 2-amino-4-({[tert-butyl(dimethyl)silyl]oxy}methyl)-1,3-thiazole-5-carboxylate
Reaction equation
[C:19]([CH3:20])([CH3:21])([CH3:22])[Si:23]([CH3:24])([CH3:25])[Cl:26].[NH2:1][c:2]1[s:3][c:4]([C:9](=[O:10])[O:11][CH2:12][CH3:13])[c:5]([CH2:7][OH:8])[n:6]1.[O:27]=[CH:28][N:29]([CH3:30])[CH3:31].[nH:14]1[cH:15][cH:16][n:17][cH:18]1>>[NH2:1][c:2]1[s:3][c:4]([C:9](=[O:10])[O:11][CH2:12][CH3:13])[c:5]([CH2:7][O:8][Si:23]([C:19]([CH3:20])([CH3:21])[CH3:22])([CH3:24])[CH3:25])[n:6]1Participants
5
Sources & evidence
- ORD record
- ord-1ec960dd00354abebf627c76d9ff25e7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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