Sodium ion → {4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-indol-1-yl}-acetic acid tert-butyl ester
Reaction equation
[C:28]([CH3:29])([CH3:30])([CH3:31])[O:32][C:33]([CH2:34][Br:35])=[O:36].[CH3:1][c:2]1[n:3][c:4](-[c:18]2[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]2)[s:5][c:6]1[CH2:7][O:8][c:9]1[c:10]2[cH:11][cH:12][nH:13][c:14]2[cH:15][cH:16][cH:17]1.[H-:37].[Na+:38].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[CH3:1][c:2]1[n:3][c:4](-[c:18]2[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]2)[s:5][c:6]1[CH2:7][O:8][c:9]1[c:10]2[cH:11][cH:12][n:13]([CH2:34][C:33]([O:32][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:36])[c:14]2[cH:15][cH:16][cH:17]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f4d6acd7f8e7457cb4d5e24ac468759c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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