1,2-Dichloroethane → 9-(3,4-Dichloro-phenylamino)-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester
Reaction equation
[C:10]([O:11][BH-:12]([O:13][C:14](=[O:15])[CH3:16])[O:17][C:18](=[O:19])[CH3:20])(=[O:21])[CH3:22].[C:28]([CH3:29])([CH3:30])([CH3:31])[O:32][C:33](=[O:34])[N:35]1[CH2:36][CH2:37][C:38]2([CH2:39][CH2:40]1)[CH2:41][CH2:42][C:43](=[O:46])[CH2:44][CH2:45]2.[CH3:24][C:25](=[O:26])[OH:27].[Cl:47][CH2:48][CH2:49][Cl:50].[NH2:1][c:2]1[cH:3][cH:4][c:5]([Cl:6])[c:7]([Cl:8])[cH:9]1.[Na+:23]>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([Cl:6])[c:7]([Cl:8])[cH:9]1)[CH:43]1[CH2:42][CH2:41][C:38]2([CH2:37][CH2:36][N:35]([C:33]([O:32][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:34])[CH2:40][CH2:39]2)[CH2:45][CH2:44]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-4d5eb08bc3b94a70aa9f3e1b016f5f24
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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