Chloride → Cyclohexyl 2-(1-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazole-4-carboxylate
Reaction equation
[Br:46][P+:47]([N:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1)([N:53]1[CH2:54][CH2:55][CH2:56][CH2:57]1)[N:58]1[CH2:59][CH2:60][CH2:61][CH2:62]1.[CH:19]1([O:25][C:26](=[O:27])[c:28]2[n:29][c:30]([CH:33]3[CH2:34][CH2:35][NH2+:36][CH2:37][CH2:38]3)[s:31][cH:32]2)[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]1.[Cl-:18].[Cl:63][CH2:64][Cl:65].[F:1][C:2]([c:3]1[n:4][n:5]([CH2:12][C:13](=[O:14])[OH:15])[c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1)([F:16])[F:17].[F:39][P-:40]([F:41])([F:42])([F:43])([F:44])[F:45]>>[F:1][C:2]([c:3]1[n:4][n:5]([CH2:12][C:13](=[O:15])[N:36]2[CH2:35][CH2:34][CH:33]([c:30]3[n:29][c:28]([C:26]([O:25][CH:19]4[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]4)=[O:27])[cH:32][s:31]3)[CH2:38][CH2:37]2)[c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1)([F:16])[F:17]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-76d91b6d7c5e4fdbb20b6cc37a2c7057
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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