Acetic Acid → N-(2-fluoro-4-chloro-5-methoxycarbonyloxyphenyl)-3,4,5,6-tetrahydrophthalimide

HRID 296887Notes

Reaction equation

HRID 296887 reaction equation
[C:15]1(=[O:25])[C:16]2=[C:17]([C:18](=[O:19])[O:20]1)[CH2:21][CH2:22][CH2:23][CH2:24]2.[CH3:27][C:28](=[O:29])[OH:30].[F:1][c:2]1[c:3]([NH2:4])[cH:5][c:6]([O:10][C:11](=[O:12])[O:13][CH3:14])[c:7]([Cl:9])[cH:8]1.[OH2:26]>>[F:1][c:2]1[c:3]([N:4]2[C:15](=[O:20])[C:16]3=[C:17]([C:18]2=[O:19])[CH2:21][CH2:22][CH2:23][CH2:24]3)[cH:5][c:6]([O:10][C:11](=[O:12])[O:13][CH3:14])[c:7]([Cl:9])[cH:8]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 962WaterHCID 124753,4,5,6-Tetrahydrophthalic anhydrideHCID 107989305-Amino-2-chloro-4-fluorophenyl methyl carbonate

Product 1

HCID 19374481N-(2-fluoro-4-chloro-5-methoxycarbonyloxyphenyl)-3,4,5,6-tetrahydrophthalimide

Sources & evidence

ORD record
ord-d26ddc0c1990462cb3dd003846fcf5c2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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