Bicarbonate Ion → 2-[4-(3-Aminopyrrolidin-1-yl)-6-fluoroquinazolin-2-yl]phenol
Reaction equation
[Cl:44][CH2:45][Cl:46].[F:1][c:2]1[cH:3][c:4]2[c:5]([N:19]3[CH2:20][CH:21]([NH:24][C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:22][CH2:23]3)[n:6][c:7](-[c:12]3[c:13]([OH:18])[cH:14][cH:15][cH:16][cH:17]3)[n:8][c:9]2[cH:10][cH:11]1.[F:32][C:33]([F:34])([F:35])[C:36]([OH:37])=[O:38].[Na+:43].[O-:39][C:40]([OH:41])=[O:42]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([N:19]3[CH2:20][CH:21]([NH2:24])[CH2:22][CH2:23]3)[n:6][c:7](-[c:12]3[c:13]([OH:18])[cH:14][cH:15][cH:16][cH:17]3)[n:8][c:9]2[cH:10][cH:11]1Participants
6
Sources & evidence
- ORD record
- ord-ab52a5df8dbb4bb487e9810d8ad1efb4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…