Dichloromethane → Benzyl 3,6-diazabicyclo[3.2.0]heptane-3-carboxylate

HRID 296933Notes

Reaction equation

HRID 296933 reaction equation
[C:1]([O:2][C:3]([NH:8][CH:9]1[CH2:10][N:11]([C:20](=[O:21])[O:22][CH2:23][c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[CH2:12][CH:13]1[CH2:14][O:4][S:5]([CH3:6])(=[O:7])=[O:15])=[O:16])([CH3:17])([CH3:18])[CH3:19].[Cl:37][CH2:38][Cl:39].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[NH:8]1[CH:9]2[CH2:10][N:11]([C:20](=[O:21])[O:22][CH2:23][c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[CH2:12][CH:13]2[CH2:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 72359917Benzyl 3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-(methylsulfonyloxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 50990188Benzyl 3,6-diazabicyclo[3.2.0]heptane-3-carboxylate

Sources & evidence

ORD record
ord-4c8afee75a5346fe83157993dd5cdfcb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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