Dichloromethane → 2-[1-(2-chlorophenyl)-1-methylethyl]-1-[3'-(methylsulfonyl)biphenyl-4-yl]-4-pyrrolidin-2-yl-1H-imidazole
Reaction equation
[Cl:1][c:2]1[c:3]([C:8]([CH3:9])([CH3:10])[c:11]2[n:12](-[c:28]3[cH:29][cH:30][c:31](-[c:34]4[cH:35][c:36]([S:40](=[O:41])(=[O:42])[CH3:43])[cH:37][cH:38][cH:39]4)[cH:32][cH:33]3)[cH:13][c:14]([CH:16]3[N:17]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:18][CH2:19][CH2:20]3)[n:15]2)[cH:4][cH:5][cH:6][cH:7]1.[Cl:51][CH2:52][Cl:53].[F:44][C:45]([F:46])([F:47])[C:48]([OH:49])=[O:50]>>[Cl:1][c:2]1[c:3]([C:8]([CH3:9])([CH3:10])[c:11]2[n:12](-[c:28]3[cH:29][cH:30][c:31](-[c:34]4[cH:35][c:36]([S:40](=[O:41])(=[O:42])[CH3:43])[cH:37][cH:38][cH:39]4)[cH:32][cH:33]3)[cH:13][c:14]([CH:16]3[NH:17][CH2:18][CH2:19][CH2:20]3)[n:15]2)[cH:4][cH:5][cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-e94f0f3943764dcc8c6b73a2048ca7ee
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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