Methanol → 3-Fluoro-4-(2-(1-propyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)aniline
Reaction equation
[BH4-:29].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:31][OH:32].[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]3[c:7]([n:8][cH:9][cH:10]2)[cH:11][c:12](-[c:14]2[n:15][cH:16][n:17]([CH2:19][CH2:20][CH3:21])[cH:18]2)[s:13]3)[cH:22][cH:23][c:24]([N+:26]([O-:27])=[O:28])[cH:25]1.[Na+:30].[Ni:38]([Cl:39])[Cl:40]>>[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]3[c:7]([n:8][cH:9][cH:10]2)[cH:11][c:12](-[c:14]2[n:15][cH:16][n:17]([CH2:19][CH2:20][CH3:21])[cH:18]2)[s:13]3)[cH:22][cH:23][c:24]([NH2:26])[cH:25]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-94d7d79af5024cba84bb8253c425e22f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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