Dichloromethane → Methyl 4-{3-[4-(biphenyl-2-ylcarbamoyloxy)piperidin-1-yl]propionylamino}-2,5-dimethylbenzoate

HRID 297685Notes

Reaction equation

HRID 297685 reaction equation
[CH:68]([N:69]([CH:70]([CH3:71])[CH3:72])[CH2:73][CH3:74])([CH3:75])[CH3:76].[Cl:65][CH2:66][Cl:67].[NH2:28][c:29]1[cH:30][c:31]([CH3:40])[c:32]([C:33](=[O:34])[O:35][CH3:36])[cH:37][c:38]1[CH3:39].[P-:41]([F:42])([F:43])([F:44])([F:45])([F:46])[F:47].[c:1]1(-[c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[c:2]([NH:7][C:8](=[O:9])[O:10][CH:11]2[CH2:12][CH2:13][N:14]([CH2:17][CH2:18][C:19](=[O:20])[OH:21])[CH2:15][CH2:16]2)[cH:3][cH:4][cH:5][cH:6]1.[n:48]1([O:49][C:50]([N:51]([CH3:52])[CH3:53])=[N+:54]([CH3:55])[CH3:56])[c:57]2[n:58][cH:59][cH:60][cH:61][c:62]2[n:63][n:64]1>>[c:1]1(-[c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[c:2]([NH:7][C:8](=[O:9])[O:10][CH:11]2[CH2:12][CH2:13][N:14]([CH2:17][CH2:18][C:19](=[O:20])[NH:28][c:29]3[cH:30][c:31]([CH3:40])[c:32]([C:33](=[O:34])[O:35][CH3:36])[cH:37][c:38]3[CH3:39])[CH2:15][CH2:16]2)[cH:3][cH:4][cH:5][cH:6]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 273299Methyl 4-amino-2,5-dimethylbenzoateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 218806073-[4-(Biphenyl-2-ylcarbamoyloxy)piperidin-1-yl]propionic Acid

Product 1

HCID 46239621Methyl 4-{3-[4-(biphenyl-2-ylcarbamoyloxy)piperidin-1-yl]propionylamino}-2,5-dimethylbenzoate

Sources & evidence

ORD record
ord-815887e78f9e4454a6385e828c1ae2a0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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