Dichloromethane → 1-isopropyl-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide

HRID 297920Notes

Reaction equation

HRID 297920 reaction equation
[CH3:1][CH:2]([CH3:3])[n:4]1[cH:5][cH:6][c:7]2[c:8]([C:32](=[O:33])[NH:34][CH2:35][c:36]3[c:37](=[O:46])[nH:38][c:39]([CH3:45])[cH:40][c:41]3[CH2:42][CH2:43][CH3:44])[cH:9][c:10](-[c:13]3[cH:14][cH:15][c:16]([N:19]4[CH2:20][CH2:21][N:22]([C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[CH2:23][CH2:24]4)[n:17][cH:18]3)[cH:11][c:12]12.[Cl:54][CH2:55][Cl:56].[F:47][C:48]([F:49])([F:50])[C:51]([OH:52])=[O:53]>>[CH3:1][CH:2]([CH3:3])[n:4]1[cH:5][cH:6][c:7]2[c:8]([C:32](=[O:33])[NH:34][CH2:35][c:36]3[c:37](=[O:46])[nH:38][c:39]([CH3:45])[cH:40][c:41]3[CH2:42][CH2:43][CH3:44])[cH:9][c:10](-[c:13]3[cH:14][cH:15][c:16]([N:19]4[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]4)[n:17][cH:18]3)[cH:11][c:12]12

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67467463HCID 67467463, compound

Product 1

HCID 674685761-isopropyl-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide

Sources & evidence

ORD record
ord-2e35cfad0e7b40a49f3ec14095d66de3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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