3-Bromopyridine → 5-(4-Chloro-3-methyl-phenyl)-3-pyridin-3-ylethynyl-7-trifluoromethyl-pyrazolo [1,5-a]pyrimidine
Reaction equation
[Br:24][c:25]1[cH:26][n:27][cH:28][cH:29][cH:30]1.[Cl:1][c:2]1[c:3]([CH3:23])[cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[n:18][cH:19][c:20]3[C:21]#[CH:22])[cH:6][cH:7]1>>[Cl:1][c:2]1[c:3]([CH3:23])[cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[n:18][cH:19][c:20]3[C:21]#[C:22][c:25]2[cH:26][n:27][cH:28][cH:29][cH:30]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-22adcc94a4f2481d98149828698f9dc1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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