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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 298046Generated: October 30, 2026

Tetrahydrofuran → 8-(2-Chloro-benzenesulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione

https://huagongshe.com/reaction/298046

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant2-Chlorobenzenesulfonyl chlorideHCID 76187—
Reactant2-(4-Trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dioneHCID 58478411—
ReactantButyllithiumHCID 178418339—
Product8-(2-Chloro-benzenesulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dioneHCID 53465275—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-a0dd1b0eb517467b9d998587226e1de9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)