Dimethyl Sulfoxide → 5-Chloro-3-(4-(4-(trifluoromethyl)pyridin-2-yloxy)phenyl)pyridin-2-amine
Reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH3:38][S:39]([CH3:40])=[O:41].[F:7][c:8]1[n:9][cH:10][cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]1.[K+:5].[K+:6].[NH2:18][c:19]1[n:20][cH:21][c:22]([Cl:32])[cH:23][c:24]1-[c:25]1[cH:26][cH:27][c:28]([OH:31])[cH:29][cH:30]1.[Na+:37].[O-:33][C:34]([OH:35])=[O:36]>>[c:8]1([O:31][c:28]2[cH:27][cH:26][c:25](-[c:24]3[c:19]([NH2:18])[n:20][cH:21][c:22]([Cl:32])[cH:23]3)[cH:30][cH:29]2)[n:9][cH:10][cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-92df655435fc457782bdae7b6d880369
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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