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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 298232Generated: October 30, 2026

Dimethyl Sulfoxide → 5-Chloro-3-(4-(4-(trifluoromethyl)pyridin-2-yloxy)phenyl)pyridin-2-amine

https://huagongshe.com/reaction/298232

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantBicarbonate IonHCID 769—
ReactantPotassium CationHCID 813—
ReactantSodium ionHCID 923—
ReactantCarbonate IonHCID 19660—
Reactant2-Fluoro-4-(trifluoromethyl)pyridineHCID 11159514—
Reactant4-(2-Amino-5-chloropyridin-3-yl)phenolHCID 66748004—
Product5-Chloro-3-(4-(4-(trifluoromethyl)pyridin-2-yloxy)phenyl)pyridin-2-amineHCID 66747922—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-92df655435fc457782bdae7b6d880369
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)