HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetate → 4-{1-Hydroxy-2-[1-(4-methoxy-benzyl)-cyclopropylamino]-ethyl}-2-hydroxymethyl-phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetate | HCID 84468 | — |
| Reactant | 1-(4-Methoxybenzyl)cyclopropanamine | HCID 23106092 | — |
| Reactant | Methyl benzyloxy-5-(2-ethoxy-2-hydroxy-acetyl)-benzoate | HCID 68858509 | — |
| Product | 4-{1-Hydroxy-2-[1-(4-methoxy-benzyl)-cyclopropylamino]-ethyl}-2-hydroxymethyl-phenol | HCID 23106126 | — |
Reaction Steps
Prepared according to general method 5 from 344 mg (1 mmol) methyl 2-benzyloxy-5-(2-ethoxy-2-hydroxy-acetyl)-benzoate and 177 mg (1 mmol) 1-(4-methoxy-benzyl)-cyclopropylamine. Yield: 123 mg (27%, trifluoroacetate); mass spectroscopy: [M+H]+=344.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423035B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-6c3bc8c1d7324940a10d9e8e4ab59f9d |
| Source note | uspto-grants-2008_09 |