Dichloromethane → (2-Chloro-phenyl)-(3-hydroxy-pyridin-2-yl)-methanone

HRID 298498Notes

Reaction equation

HRID 298498 reaction equation
[Cl:32][CH2:33][Cl:34].[Cl:8][c:9]1[c:10]([C:15](=[O:16])[c:17]2[n:18][cH:19][cH:20][cH:21][c:22]2[O:23][CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:29])([CH3:30])[CH3:31])[cH:11][cH:12][cH:13][cH:14]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[Cl:8][c:9]1[c:10]([C:15](=[O:16])[c:17]2[n:18][cH:19][cH:20][cH:21][c:22]2[OH:23])[cH:11][cH:12][cH:13][cH:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 69153886(2-Chloro-phenyl)-[3-(2-trimethylsilanyl-ethoxymethoxy)-pyridin-2-yl]-methanone

Product 1

HCID 69154628(2-Chloro-phenyl)-(3-hydroxy-pyridin-2-yl)-methanone

Sources & evidence

ORD record
ord-a3452b327d9f4148bff9949a73203065
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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