Hydrochloric Acid → N-(6-isopropylpyridin-3-yl)-N-({1-[(4-methylpyridin-2-yl)methyl]pyrazol-4-yl}methyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide

HRID 298709Notes

Reaction equation

HRID 298709 reaction equation
[CH2:42]([Cl:43])[Cl:44].[CH2:50]([N+:51]([CH2:52][CH2:53][CH2:54][CH3:55])([CH2:56][CH2:57][CH2:58][CH3:59])[CH2:60][CH2:61][CH2:62][CH3:63])[CH2:64][CH2:65][CH3:66].[CH:2]([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([N:11]([C:12](=[O:13])[CH:14]2[CH2:15][CH2:16][CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][c:23]32)[CH2:24][c:25]2[cH:26][n:27][nH:28][cH:29]2)[cH:9][n:10]1.[Cl:31][CH2:32][c:33]1[n:34][cH:35][cH:36][c:37]([CH3:39])[cH:38]1.[ClH:1].[ClH:30].[Na+:41].[OH-:40].[S:45]([O-:46])([OH:47])(=[O:48])=[O:49]>>[CH:2]([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([N:11]([C:12](=[O:13])[CH:14]2[CH2:15][CH2:16][CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][c:23]32)[CH2:24][c:25]2[cH:26][n:27][n:28]([CH2:32][c:33]3[n:34][cH:35][cH:36][c:37]([CH3:39])[cH:38]3)[cH:29]2)[cH:9][n:10]1

Participants

9

Reactant 8

HCID 313Hydrochloric Acid2×HCID 923Sodium ionHCID 961HydroxideHCID 6344DichloromethaneHCID 16028TetrabutylammoniumHCID 61778Sulfate, hydrogenHCID 126752612-(Chloromethyl)-4-methylpyridineHCID 59597448N-(6-propan-2-yl-3-pyridinyl)-N-(1H-pyrazol-4-ylmethyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide

Product 1

HCID 59597447N-(6-isopropylpyridin-3-yl)-N-({1-[(4-methylpyridin-2-yl)methyl]pyrazol-4-yl}methyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide

Sources & evidence

ORD record
ord-8cece96610dc4dc7a8ad6bd5d808bbe1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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