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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29905Generated: October 28, 2026

4-Fluorobenzyl bromide → 4-[(4-Fluorobenzyl)oxy]-6-isopropyl-2-(3-nitrophenyl)pyrimidine

https://huagongshe.com/reaction/29905

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzyl bromideHCID 68021—
ReactantHCID 178439455HCID 178439455—
Product4-[(4-Fluorobenzyl)oxy]-6-isopropyl-2-(3-nitrophenyl)pyrimidineHCID 9976224—

Reaction Steps

The title compound was prepared from 6-isopropyl-2-(3-nitro-phenyl)-pyrimidin-4-ol (which was obtained in Intermediate 8) and 4-fluorobenzyl bromide according to Method A; LC retention time 4.01 min: MS: m/z (ESI) 368 (M+H)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423044B2
Source datasetuspto-grants-2008_09
ORD IDord-5baea2d5281d4f12a4851b9d66e69b6a
Source noteuspto-grants-2008_09