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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29906Generated: October 26, 2026

4-(Bromomethyl)benzonitrile → 4-({[2-(3,5-Dichlorophenyl)-6-isopropylpyrimidin-4-yl]oxy}methyl)benzonitrile

https://huagongshe.com/reaction/29906

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Bromomethyl)benzonitrileHCID 86996—
ReactantHCID 178439458HCID 178439458—
Product4-({[2-(3,5-Dichlorophenyl)-6-isopropylpyrimidin-4-yl]oxy}methyl)benzonitrileHCID 11741559—

Reaction Steps

The title compound was prepared from 2-(3,5-dichloro-phenyl)-6-isopropyl-pyrimidin-4-ol (which was obtained in Intermediate 6) and 4-cyanobenzyl bromide according to Method A; LC retention time 4.22 min; MS: m/z (ESI) 398 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423044B2
Source datasetuspto-grants-2008_09
ORD IDord-52bde15521394de9bf08913cd8331e89
Source noteuspto-grants-2008_09