Dimethyl Sulfoxide → (+/-)-3-[7-[3-(2-dimethylamino-ethyl)-phenylamino]-3-(4-methoxy-phenyl)-4-methyl-2-oxo-3,4-dihydro-2H-pyrimido[4,5-d]pyrimidin-1-yl]-benzamide
Reaction equation
[CH3:1][N:2]([CH2:3][CH2:4][c:5]1[cH:6][c:7]([NH:11][c:12]2[n:13][cH:14][c:15]3[c:16]([n:17]2)[N:18]([c:32]2[cH:33][c:34]([C:35]#[N:36])[cH:37][cH:38][cH:39]2)[C:19](=[O:31])[N:20]([c:23]2[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]2)[CH:21]3[CH3:22])[cH:8][cH:9][cH:10]1)[CH3:40].[CH3:53][S:54](=[O:55])[CH3:56].[N:43]#[C:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1.[Na+:42].[OH-:41].[OH:51][OH:52]>>[CH3:1][N:2]([CH2:3][CH2:4][c:5]1[cH:6][c:7]([NH:11][c:12]2[n:13][cH:14][c:15]3[c:16]([n:17]2)[N:18]([c:32]2[cH:33][c:34]([C:35]([NH2:36])=[O:41])[cH:37][cH:38][cH:39]2)[C:19](=[O:31])[N:20]([c:23]2[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]2)[CH:21]3[CH3:22])[cH:8][cH:9][cH:10]1)[CH3:40]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-8797818a627b4dfba52eaff690e8fd32
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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