1-Butanol → 5-chloro-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[1-(3,5-difluoro-2-pyridinyl)ethyl]pyrimidine-2,4-diamine
Reaction equation
[CH2:38]([OH:39])[CH2:40][CH2:41][CH3:42].[CH:29]([N:30]([CH2:31][CH3:32])[CH:33]([CH3:34])[CH3:35])([CH3:36])[CH3:37].[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:17])[c:6]([NH:8][c:9]2[n:10][nH:11][c:12]([CH:14]3[CH2:15][CH2:16]3)[cH:13]2)[n:7]1.[F:18][c:19]1[c:20]([CH:26]([CH3:27])[NH2:28])[n:21][cH:22][c:23]([F:25])[cH:24]1>>[c:2]1([NH:28][CH:26]([c:20]2[c:19]([F:18])[cH:24][c:23]([F:25])[cH:22][n:21]2)[CH3:27])[n:3][cH:4][c:5]([Cl:17])[c:6]([NH:8][c:9]2[n:10][nH:11][c:12]([CH:14]3[CH2:15][CH2:16]3)[cH:13]2)[n:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-bf43113dfadb4bfc866ade819f62f90f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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