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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29914Generated: October 26, 2026

Methyl 4-(bromomethyl)benzoate bromide → 4-({[2-(3,5-Dichlorophenyl)-6-isopropylpyrimidin-4-yl]oxy}methyl)benzoic acid

https://huagongshe.com/reaction/29914

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(bromomethyl)benzoate bromideHCID 86592754—
ReactantHCID 178439458HCID 178439458—
Product4-({[2-(3,5-Dichlorophenyl)-6-isopropylpyrimidin-4-yl]oxy}methyl)benzoic acidHCID 10070570—

Reaction Steps

The title compound was prepared from 2-(3,5-dichloro-phenyl)-6-isopropyl-pyrimidin-4-ol (which was obtained in Intermediate 6) and methyl 4-(bromomethyl)benzoate bromide according to Method A and Method B; LC retention time 4.11 min; MS: m/z (ESI) 415 (M−H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423044B2
Source datasetuspto-grants-2008_09
ORD IDord-e9a48ffa529e4ecc85d749ab8be3e47e
Source noteuspto-grants-2008_09