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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29916Generated: October 27, 2026

Methyl 4-(bromomethyl)benzoate → 4-({[6-Isopropyl-2-(3-nitrophenyl)pyrimidin-4-yl]oxy}methyl)benzoic acid

https://huagongshe.com/reaction/29916

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(bromomethyl)benzoateHCID 256687—
ReactantHCID 178439455HCID 178439455—
Product4-({[6-Isopropyl-2-(3-nitrophenyl)pyrimidin-4-yl]oxy}methyl)benzoic acidHCID 69199289—

Reaction Steps

The title compound was prepared from 6-isopropyl-2-(3-nitro-phenyl)-pyrimidin-4-ol (which was obtained in Intermediate 8) and methyl 4-(bromomethyl)benzoate according to Method A and Method B; LC retention time 3.40 min; MS: m/z (ESI) 394 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423044B2
Source datasetuspto-grants-2008_09
ORD IDord-e161ff5da5ca4b65b5f7decd58f38b5a
Source noteuspto-grants-2008_09