Hydrazine hydrate (1:1) → 7-Methoxy-4-(thiophen-2-yl)-2H-phthalazin-1-one

HRID 29931Notes

Reaction equation

HRID 29931 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:12]([C:14]2[S:15][CH:16]=[CH:17][CH:18]=2)=O)=[C:7]([CH:11]=1)[C:8](O)=[O:9].O.[NH2:20][NH2:21]>>[CH3:1][O:2][C:3]1[CH:11]=[C:7]2[C:6]([C:12]([C:14]3[S:15][CH:16]=[CH:17][CH:18]=3)=[N:20][NH:21][C:8]2=[O:9])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 692129835-Methoxy-2-(thiophene-2-carbonyl)benzoic acid

Product 1

HCID 692118337-Methoxy-4-(thiophen-2-yl)-2H-phthalazin-1-one

Procedure

This compound is obtained according to the procedure described in 1.2. by reacting unpurified 5-methoxy-2-(thiophene-2-carbonyl)benzoic acid with hydrazine hydrate.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-188884eafdca45a39b599ec076508c09
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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