HRID29950

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11195823

未命名化合物

结构：COc1ccc(-c2nnc(Cl)c3cc(OC)cc(OC)c23)cc1

HCID86075292

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(-c2nnc(NC3CCN(Cc4ccc5ccccc5c4)CC3)c3cc(OC)cc(OC)c23)cc1.Cl.Cl

HCID69209373

未命名化合物

PROCEDURE

实验过程

This compound is obtained according to the procedure described in 2.4 by reacting 4-chloro-6,8-dimethoxy-1-(4-methoxyphenyl)phthalazine described in 2.3 with 4-amino-1-(naphthalen-2-ylmethyl)piperidine. On treatment with hydrochloric ether, a precipitate forms, which is filtered off, washed with ethyl ether and dried under reduced pressure. The hydrochloride obtained is in the form of a white solid.

WORKUP

后处理

customThis compound is obtained
filtrationOn treatment with hydrochloric ether, a precipitate forms, which is filtered off
washwashed with ethyl ether
customdried under reduced pressure

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d61b05d1654d40dab85dde057c16e206
来源数据集: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07423030B2
来源说明: uspto-grants-2008_09

反应 SMILES

[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([O:14][CH3:15])[CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[C:5]([C:16]2[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=2)=[N:4][N:3]=1.[NH2:24][CH:25]1[CH2:30][CH2:29][N:28]([CH2:31][C:32]2[CH:41]=[CH:40][C:39]3[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=3)[CH:33]=2)[CH2:27][CH2:26]1>>[ClH:1].[ClH:1].[CH3:15][O:14][C:7]1[CH:8]=[C:9]([O:12][CH3:13])[CH:10]=[C:11]2[C:6]=1[C:5]([C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=1)=[N:4][N:3]=[C:2]2[NH:24][CH:25]1[CH2:26][CH2:27][N:28]([CH2:31][C:32]2[CH:41]=[CH:40][C:39]3[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=3)[CH:33]=2)[CH2:29][CH2:30]1