Phosphorus oxychloride → 1-Chloro-4-ethyl-7-methoxyphthalazine

HRID 29961Notes

Reaction equation

[CH2:1]([C:3]1[C:12]2[C:7](=[CH:8][C:9]([O:13][CH3:14])=[CH:10][CH:11]=2)[C:6](=O)[NH:5][N:4]=1)[CH3:2].P(Cl)(Cl)([Cl:18])=O>>[Cl:18][C:6]1[C:7]2[C:12](=[CH:11][CH:10]=[C:9]([O:13][CH3:14])[CH:8]=2)[C:3]([CH2:1][CH3:2])=[N:4][N:5]=1

Participants

Reactant 2

HCID 24813Phosphorus oxychloride

HCID 576917044-ethyl-7-methoxy-2H-phthalazin-1-one

Product 1

HCID 576917031-Chloro-4-ethyl-7-methoxyphthalazine

Procedure

This compound is obtained according to the procedure described in 1.3. by reacting 4-ethyl-7-methoxy-2H-phthalazin-1-one with phosphoryl chloride.

Workup

customThis compound is obtained

Sources & evidence

ORD record: ord-3bb070770c5c4ed2a895bf8e65ba2ce6
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07423030B2

Reaction notes

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