Hydrazine hydrate (1:1) → 4-benzyl-7-methoxy-2H-phthalazin-1-one

HRID 29963Notes

Reaction equation

HRID 29963 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:12](=O)[CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:7]([CH:11]=1)[C:8](O)=[O:9].O.[NH2:22][NH2:23]>>[CH2:13]([C:12]1[C:6]2[C:7](=[CH:11][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[C:8](=[O:9])[NH:23][N:22]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 69211467HCID 69211467, compound

Product 1

HCID 692088754-benzyl-7-methoxy-2H-phthalazin-1-one

Procedure

This compound is obtained according to the procedure described in 1.2. by reacting unpurified 5-methoxy-2-(phenylacetyl)benzoic acid with hydrazine hydrate.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-543dcc82ba284e38a9898421d91dcbdf
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

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