Phosphorus oxychloride → 1-Chloro-5,7-dimethoxy-4-ethylphthalazine

HRID 29972Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:12]=[C:11]([O:13][CH3:14])[CH:10]=[C:9]2[C:4]=1[C:5]([CH2:16][CH3:17])=[N:6][NH:7][C:8]2=O.P(Cl)(Cl)([Cl:20])=O>>[Cl:20][C:8]1[C:9]2[C:4](=[C:3]([O:2][CH3:1])[CH:12]=[C:11]([O:13][CH3:14])[CH:10]=2)[C:5]([CH2:16][CH3:17])=[N:6][N:7]=1

Participants

Reactant 2

HCID 24813Phosphorus oxychloride

HCID 69209368HCID 69209368, compound

Product 1

HCID 866122191-Chloro-5,7-dimethoxy-4-ethylphthalazine

Procedure

This compound is obtained according to the procedure described in 1.3. by reacting 5,7-dimethoxy-4-ethyl-2H-phthalazin-1-one with phosphoryl chloride.

Workup

customThis compound is obtained

Sources & evidence

ORD record: ord-c65265230f564feb9a793b2bc6ea9eb5
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07423030B2

Reaction notes

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