Phosphorus oxychloride → 4-(1,3-Benzodioxol-5-yl)-1-chloro-7-methoxyphthalazine

HRID 29984Notes

Reaction equation

[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]3[C:19]4[C:14](=[CH:15][C:16]([O:20][CH3:21])=[CH:17][CH:18]=4)[C:13](=O)[NH:12][N:11]=3)=[CH:9][C:4]=2[O:3][CH2:2]1.P(Cl)(Cl)([Cl:25])=O>>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]3[C:19]4[C:14](=[CH:15][C:16]([O:20][CH3:21])=[CH:17][CH:18]=4)[C:13]([Cl:25])=[N:12][N:11]=3)=[CH:9][C:4]=2[O:3][CH2:2]1

Participants

Reactant 2

HCID 24813Phosphorus oxychloride

HCID 692126624-(1,3-benzodioxol-5-yl)-7-methoxy-2H-phthalazin-1-one

Product 1

HCID 866122214-(1,3-Benzodioxol-5-yl)-1-chloro-7-methoxyphthalazine

Procedure

This compound is obtained according to the procedure described in 1.3. by reacting 4-(1,3-benzodioxol-5-yl)-7-methoxy-2H-phthalazin-1-one with phosphoryl chloride.

Workup

customThis compound is obtained

Sources & evidence

ORD record: ord-dff6382e060a4ee68a1c9e8ff707cc6f
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07423030B2

Reaction notes

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