Dichloromethane → 7-Chloro-5-hydroxy-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-isoindol-1-one
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([O:24][CH2:25][c:26]2[cH:27][cH:28][c:29]([O:30][CH3:31])[cH:32][cH:33]2)[cH:5][c:6]2[c:10]1[C:9](=[O:11])[N:8]([CH2:12][c:13]1[cH:14][cH:15][c:16]([O:19][C:20]([F:21])([F:22])[F:23])[cH:17][cH:18]1)[CH2:7]2.[Cl:41][CH2:42][Cl:43].[OH:34][C:35]([C:36]([F:37])([F:38])[F:39])=[O:40]>>[Cl:1][c:2]1[cH:3][c:4]([OH:24])[cH:5][c:6]2[c:10]1[C:9](=[O:11])[N:8]([CH2:12][c:13]1[cH:14][cH:15][c:16]([O:19][C:20]([F:21])([F:22])[F:23])[cH:17][cH:18]1)[CH2:7]2Participants
4
Sources & evidence
- ORD record
- ord-bc1595d527554539988401cdedf962f1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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