Dimethyl Sulfoxide → 4-(7-Piperazin-1-yl-quinazolin-4-yl)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[N:14]1[CH2:15][CH2:16][CH:17]([c:20]2[n:21][cH:22][n:23][c:24]3[cH:25][c:26]([F:30])[cH:27][cH:28][c:29]23)[CH2:18][CH2:19]1.[CH2:1]1[CH2:2][NH:3][CH2:4][CH2:5][NH:6]1.[CH3:31][S:32]([CH3:33])=[O:34].[OH2:35]>>[CH2:1]1[CH2:2][N:3]([c:26]2[cH:25][c:24]3[n:23][cH:22][n:21][c:20]([CH:17]4[CH2:16][CH2:15][N:14]([C:12]([O:11][C:7]([CH3:8])([CH3:9])[CH3:10])=[O:13])[CH2:19][CH2:18]4)[c:29]3[cH:28][cH:27]2)[CH2:4][CH2:5][NH:6]1Participants
5
Sources & evidence
- ORD record
- ord-ec5f71bc5479416480843ba06b48a9d3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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