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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 30020Generated: October 30, 2026

2-Bromo-5-methoxybenzoic acid → 2-(2,5-Dimethoxybenzoyl)-5-methoxybenzoic acid

https://huagongshe.com/reaction/30020

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-5-methoxybenzoic acidHCID 89906—
ReactantHCID 18931310HCID 18931310—
ReactantButyllithiumHCID 178418339—
Product2-(2,5-Dimethoxybenzoyl)-5-methoxybenzoic acidHCID 69212244—

Reaction Steps

This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with 2,5-dimethoxy-N-methoxy-N-methylbenzamide. It is crystallized from diisopropyl ether.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423030B2
Source datasetuspto-grants-2008_09
ORD IDord-dd638509591b49f5843084af3c32ff33
Source noteuspto-grants-2008_09