HRID300230

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID235516

4-amino-N-methylbenzamide

C8H10N2O

结构：O=C(O)CC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1

HCID57875811

未命名化合物

PRODUCTS

生成物

结构：CNC(=O)c1ccc(NC(=O)CC(=O)N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cc1

HCID44231328

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4830832f434d4430ad8148053d703ca4
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (8/10)

反应 SMILES

[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[NH:8][CH3:9])[cH:10][cH:11]1.[O:12]=[C:13]([CH2:14][C:15](=[O:16])[OH:17])[N:18]1[CH2:19][CH2:20][N:21]([C:24]([c:25]2[c:26]([C:31]([F:32])([F:33])[F:34])[cH:27][cH:28][cH:29][cH:30]2)=[O:35])[CH2:22][CH2:23]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[NH:8][CH3:9])[cH:10][cH:11]1)[C:15]([CH2:14][C:13](=[O:12])[N:18]1[CH2:19][CH2:20][N:21]([C:24]([c:25]2[c:26]([C:31]([F:32])([F:33])[F:34])[cH:27][cH:28][cH:29][cH:30]2)=[O:35])[CH2:22][CH2:23]1)=[O:16]