Hydrazine hydrate (1:1) → 7-fluoro-4-(4-fluorophenyl)-2H-phthalazin-1-one

HRID 30031Notes

Reaction equation

HRID 30031 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:11](=O)[C:12]2[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=2)=[C:6]([CH:10]=1)[C:7](O)=[O:8].O.[NH2:21][NH2:22]>>[F:1][C:2]1[CH:10]=[C:6]2[C:5]([C:11]([C:12]3[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=3)=[N:21][NH:22][C:7]2=[O:8])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 27744695-fluoro-2-(4-fluorobenzoyl)benzoic Acid

Product 1

HCID 692094417-fluoro-4-(4-fluorophenyl)-2H-phthalazin-1-one

Procedure

This compound is obtained according to the procedure described in 1.2. by reacting 5-fluoro-2-(4-fluorobenzoyl)benzoic acid with hydrazine hydrate.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-55caedc6859a4d4583280d5bdbf33e97
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

Loading…