Phosphorus oxychloride → 4-(Biphenyl-4-yl)-1-chloro-7-methoxyphthalazine

HRID 30037Notes

Reaction equation

HRID 30037 reaction equation
[C:1]1([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:6]=[CH:5][C:4]([C:7]2[C:16]3[C:11](=[CH:12][C:13]([O:17][CH3:18])=[CH:14][CH:15]=3)[C:10](=O)[NH:9][N:8]=2)=[CH:3][CH:2]=1.P(Cl)(Cl)([Cl:28])=O>>[C:1]1([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:6]=[CH:5][C:4]([C:7]2[C:16]3[C:11](=[CH:12][C:13]([O:17][CH3:18])=[CH:14][CH:15]=3)[C:10]([Cl:28])=[N:9][N:8]=2)=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 692130064-(biphenyl-4-yl)-7-methoxy-2H-phthalazin-1-one

Product 1

HCID 866122334-(Biphenyl-4-yl)-1-chloro-7-methoxyphthalazine

Procedure

This compound is obtained according to the procedure described in 1.3. by reacting 4-(biphenyl-4-yl)-7-methoxy-2H-phthalazin-1-one with phosphoryl chloride.

Workup

  1. customThis compound is obtained

Sources & evidence

ORD record
ord-214f01e6be4a443190aae6750488adf4
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Reaction notes

Loading…