Phosphorus oxychloride → 1-Chloro-4-(3,4-dimethylphenyl)-7-methoxyphthalazine

HRID 30040Notes

Reaction equation

[CH3:1][C:2]1[CH:3]=[C:4]([C:9]2[C:18]3[C:13](=[CH:14][C:15]([O:19][CH3:20])=[CH:16][CH:17]=3)[C:12](=O)[NH:11][N:10]=2)[CH:5]=[CH:6][C:7]=1[CH3:8].P(Cl)(Cl)([Cl:24])=O>>[Cl:24][C:12]1[C:13]2[C:18](=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=2)[C:9]([C:4]2[CH:5]=[CH:6][C:7]([CH3:8])=[C:2]([CH3:1])[CH:3]=2)=[N:10][N:11]=1

Participants

Reactant 2

HCID 24813Phosphorus oxychloride

HCID 692123094-(3,4-dimethylphenyl)-7-methoxy-2H-phthalazin-1-one

Product 1

HCID 877347491-Chloro-4-(3,4-dimethylphenyl)-7-methoxyphthalazine

Procedure

This compound is obtained according to the procedure described in 1.3. by reacting 4-(3,4-dimethylphenyl)-7-methoxy-2H-phthalazin-1-one with phosphoryl chloride.

Workup

customThis compound is obtained

Sources & evidence

ORD record: ord-2ca10b9408b749c4a9747d6903bacda2
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07423030B2

Reaction notes

Loading…