Phosphorus oxychloride → 4-(4-Bromophenyl)-1-chloro-7-methoxyphthalazine

HRID 30053Notes

Reaction equation

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:18][CH3:19])=[CH:15][CH:16]=3)[C:11](=O)[NH:10][N:9]=2)=[CH:4][CH:3]=1.P(Cl)(Cl)([Cl:23])=O>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:18][CH3:19])=[CH:15][CH:16]=3)[C:11]([Cl:23])=[N:10][N:9]=2)=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 24813Phosphorus oxychloride

HCID 69209026HCID 69209026, compound

Product 1

HCID 877356424-(4-Bromophenyl)-1-chloro-7-methoxyphthalazine

Procedure

This compound is obtained according to the procedure described in 1.3. by reacting 4-(4-bromophenyl)-7-methoxy-2H-phthalazin-1-one with phosphoryl chloride.

Workup

customThis compound is obtained

Sources & evidence

ORD record: ord-f6c43f40b20b48c3962ca87d58999bca
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07423030B2

Reaction notes

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