Hydrochloric Acid → N-[2-Amino-6-chloro-4-pyrimidinyl]-N-[3-fluoro-4-(1H-indazol-5-yloxy)phenyl]amine
Reaction equation
[C:29](=[O:30])([OH:31])[O-:32].[Cl:19][c:20]1[n:21][c:22]([NH2:27])[n:23][c:24]([Cl:26])[cH:25]1.[ClH:28].[NH2:1][c:2]1[cH:3][c:4]([F:18])[c:5]([O:6][c:7]2[cH:8][c:9]3[cH:10][n:11][nH:12][c:13]3[cH:14][cH:15]2)[cH:16][cH:17]1.[Na+:33].[OH2:34]>>[NH:1]([c:2]1[cH:3][c:4]([F:18])[c:5]([O:6][c:7]2[cH:8][c:9]3[cH:10][n:11][nH:12][c:13]3[cH:14][cH:15]2)[cH:16][cH:17]1)[c:24]1[n:23][c:22]([NH2:27])[n:21][c:20]([Cl:19])[cH:25]1Participants
7
Sources & evidence
- ORD record
- ord-3383ee8c4e0b4dd6a8d325582bfb112e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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