Triphenylphosphine → 6-[6-(1-Ethoxy-vinyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl]-5,7-difluoro-quinoline
Reaction equation
[CH2:24]([Sn:25]([CH2:26][CH2:27][CH2:28][CH3:34])([C:29](=[CH2:30])[O:31][CH2:32][CH3:33])[CH2:35][CH2:36][CH2:37][CH3:38])[CH2:39][CH2:40][CH3:41].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[n:6]([n:7]1)[c:8]([CH2:11][c:12]1[c:13]([F:23])[c:14]3[cH:15][cH:16][cH:17][n:18][c:19]3[cH:20][c:21]1[F:22])[n:9][n:10]2.[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1.[Pd:48]([Cl:49])[Cl:50].[c:51]1([P:52]([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)[cH:65][cH:66][cH:67][cH:68][cH:69]1.[c:70]1([P:71]([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[cH:84][cH:85][cH:86][cH:87][cH:88]1>>[c:2]1([C:29](=[CH2:30])[O:31][CH2:32][CH3:33])[cH:3][cH:4][c:5]2[n:6]([n:7]1)[c:8]([CH2:11][c:12]1[c:13]([F:23])[c:14]3[cH:15][cH:16][cH:17][n:18][c:19]3[cH:20][c:21]1[F:22])[n:9][n:10]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b0dc8f2f5ec5472198ac58efcf14708a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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