Dichloromethane → 6-[(cyclopropylmethyl)(propyl)amino]-N-{4-[(2-oxo-1,3-oxazolidin-4-yl)methyl]phenyl}pyrimidine-4-carboxamide

HRID 301069Notes

Reaction equation

HRID 301069 reaction equation
[CH:18]([N:19]([CH:20]([CH3:21])[CH3:22])[CH2:23][CH3:24])([CH3:25])[CH3:26].[CH:1]1([CH2:4][N:5]([c:6]2[cH:7][c:8]([C:12](=[O:13])[OH:14])[n:9][cH:10][n:11]2)[CH2:15][CH2:16][CH3:17])[CH2:2][CH2:3]1.[Cl:27][C:28]([O:29][CH3:30])=[O:31].[Cl:46][CH2:47][Cl:48].[O:32]=[C:33]1[O:34][CH2:35][CH:36]([CH2:38][c:39]2[cH:40][cH:41][c:42]([NH2:43])[cH:44][cH:45]2)[NH:37]1>>[CH:1]1([CH2:4][N:5]([c:6]2[cH:7][c:8]([C:12](=[O:14])[NH:43][c:42]3[cH:41][cH:40][c:39]([CH2:38][CH:36]4[CH2:35][O:34][C:33](=[O:32])[NH:37]4)[cH:45][cH:44]3)[n:9][cH:10][n:11]2)[CH2:15][CH2:16][CH3:17])[CH2:2][CH2:3]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 6586Methyl chloroformateHCID 81531DiisopropylethylamineHCID 11842283(R)-4-(4-Aminobenzyl)-2-oxazolidinoneHCID 594470006-[(Cyclopropylmethyl)(propyl)amino]pyrimidine-4-carboxylic acid

Product 1

HCID 594470266-[(cyclopropylmethyl)(propyl)amino]-N-{4-[(2-oxo-1,3-oxazolidin-4-yl)methyl]phenyl}pyrimidine-4-carboxamide

Sources & evidence

ORD record
ord-cc390e0b32234069bc546addbae5a826
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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